海外トピックス

  • 妊娠前の食事が生まれてくる子供に与える影響

    2011:07:08:00:05:00
  • 2011年07月08日

マウスの実験ではあるが、妊娠前の食事にタンパク質が足りないと、生まれてくる子供に低体重や2型糖尿病、肥満のリスクが高くなる可能性がある。この研究はUniversity of Aarthusの研究者らによってSociety for Experimental Biologyの学術総会で発表された。 
 
1-Jul-2011

 

 

Public release date: 1-Jul-2011

Contact: Daisy Brickhill

brickhil@exchange.lancs.ac.uk
07-896-317-921
Society for Experimental Biology  

Pre-pregnancy diet affects the health of future offspring

Poor maternal diet before conception can result in offspring with reduced birth weights and increased risk of developing type II diabetes and obesity.

This work, which is being presented at the Society for Experimental Biology Annual Conference in Glasgow on Saturday the 2nd of July, used an animal model to illustrate the importance of maternal diet even before pregnancy begins.

During the study mice that were fed a low protein diet for ten weeks before conception (but had a normal diet during pregnancy) gave birth to offspring that had lower birth weights, showed catch-up growth after weaning and increased insulin sensitivity.

These effects combined can lead to problems later in life. MSc researcher, Ms Anete Dudele, from the University of Aarhus, explains: "Low birth weight and catch-up growth is associated with enhanced insulin-sensitivity in young adults, this then deteriorates into insulin resistance and type II diabetes with increased age. There is also evidence that male offspring are more likely to develop obesity."

Humans and mice respond in the same way to poor diet during pregnancy; their offspring show low birth weights and increased risk of obesity, type II diabetes and cardiovascular disease. "If humans respond in the same way as mice to pre-conception diet as well then women should not only consider what they eat during pregnancy but also before pregnancy if they want to reduce the risk of their future children acquiring lifestyle diseases," says Ms. Dudele.

Cardiovascular disease is often associated with obesity and type II diabetes and future research by the team will determine whether offspring born to mothers who had poor pre-conception diets are predisposed to these types of problems as well.


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